area 25
Acronym: 25
The term area 25 (25) refers to a part of anterior cingulate cortex (ACC) identified histologically by multiple stains in the human, macaque, rat and mouse ( Vogt-2013 ). It is agranular cortex located, in the human, in the subcallosal gyrus (SBG) ventral to the genu of the corpus callosum (gcc).
      In the macaque it is located similarly ventral to the gcc, but in the anterior cingulate gyrus (ACG); the macaque lacks a SBG distinct from the ACG ( Martin-2000 ).
      In the rat and mouse 25 is located rostral to the gcc, ( Vogt-2013 ).
      Major iinputs to 25 in the macaque
     . Major outputs from 25 in the macaque, rat, and mouse are to nucleus accumbens (ACB) ( Wise-2008 ).
      Functionally 25 is important in the control of autonomic nervous system (ANS). electrical stimulation of 25 is rewarding in the macaque ( Bowden-2022 ) but has a low concentration of dopamine relative to other areas of ACC, so it is probably not directly engaged in adaptive strengthening of synapses.

Also known as: No other name for this structure has appeared in PubMed.NeuroNames ID : 3490


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