Source: Wise-2008



Forward Frontal Fields: Phylogeny and Fundamental Function

Wise SP

Wise SP.(2008) Forward frontal fields: phylogeny and fundamental function. Trends Neurosci. 31:12:599-608. doi: 10.1016/j.tins.2008.08.008. ABSTRACT The largest part of the primate prefrontal cortex has no homologue in other mammals. Accordingly, it probably confers some advantage that other mammals either lack or attain another way. Yet this advantage remains enigmatic. Not so for other parts of cortex. For example, certain visual areas encode, represent and store knowledge about objects. By analogy, perhaps the primate prefrontal cortex encodes, represents and stores knowledge about behaviors, including the consequences of doing (or not doing) something in complex and challenging situations. The long list of functions often attributed to prefrontal cortex may all contribute to knowing what to do and what will happen when rare risks arise or outstanding opportunities knock





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